3SYR

Glycogen phosphorylase b in complex with beta-D-glucopyranonucleoside 5-fluorouracil

Summary for 3SYR

Entry DOI	10.2210/pdb3syr/pdb
Related	3SYM
Descriptor	Glycogen phosphorylase, muscle form, 5-fluoro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione (3 entities in total)
Functional Keywords	alpha and beta protein (a/b), transferase, muscle, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
Total number of polymer chains	1
Total formula weight	97811.54
Authors	Skamnaki, V.T.,Kantsadi, A.L.,Kontou, M.,Leonidas, D.D. (deposition date: 2011-07-18, release date: 2012-02-15, Last modification date: 2020-07-29)
Primary citation	Manta, S.,Xipnitou, A.,Kiritsis, C.,Kantsadi, A.L.,Hayes, J.M.,Skamnaki, V.T.,Lamprakis, C.,Kontou, M.,Zoumpoulakis, P.,Zographos, S.E.,Leonidas, D.D.,Komiotis, D. 3'-Axial CH(2) OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM-PBSA Calculations Suggest Why. Chem.Biol.Drug Des., 79:663-673, 2012 Cited by PubMed: 22296957 DOI: 10.1111/j.1747-0285.2012.01349.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation