3S5A

ABH2 cross-linked to undamaged dsDNA-2 with cofactors

Summary for 3S5A

• Entry DOI: 10.2210/pdb3s5a/pdb
• Related: 3BTY 3S57
• Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, 5'-D(*CP*TP*GP*TP*CP*TP*CP*AP*CP*TP*GP*TP*CP*G)-3', 5'-D(*TP*CP*GP*AP*CP*AP*GP*TP*GP*AP*GP*AP*CP*A)-3', ... (8 entities in total)
• Functional Keywords: protein-dna complex, double helix, jelly-roll fold, dioxygenase, dna binding, cross-linking, oxidoreductase-dna complex, oxidoreductase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q6NS38
• Total number of polymer chains: 3
• Total formula weight: 32357.66

Authors

Yi, C.,Chen, B.,Qi, B.,Ramirez, B.,Zhang, W.,Jia, G.,Zhang, L.,Li, C.Q.,Dinner, A.R.,Yang, C.-G.,He, C. (deposition date: 2011-05-21, release date: 2012-06-06, Last modification date: 2024-03-20)

• Primary citation: Yi, C.,Chen, B.,Qi, B.,Zhang, W.,Jia, G.,Zhang, L.,Li, C.J.,Dinner, A.R.,Yang, C.G.,He, C.; Duplex interrogation by a direct DNA repair protein in search of base damage; Nat.Struct.Mol.Biol., 19:671-676, 2012; PubMed: 22659876; DOI: 10.1038/nsmb.2320

Experimental method

X-RAY DIFFRACTION (1.7 Å)