3RMC

Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol

Summary for 3RMC

• Entry DOI: 10.2210/pdb3rmc/pdb
• Related: 2DY4 3RMA 3RMB 3RMD
• Descriptor: DNA polymerase, DNA (5'-D(*CP*GP*TP*(CTG)P*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*CP*A)-3'), ... (4 entities in total)
• Functional Keywords: dna lesion, thymine glycol, protein-dna complex, transferase-dna complex, transferase/dna
• Biological source: Enterobacteria phage RB69
• Total number of polymer chains: 12
• Total formula weight: 459667.88

Authors

Aller, P.,Duclos, S.,Wallace, S.S.,Doublie, S. (deposition date: 2011-04-20, release date: 2011-08-10, Last modification date: 2023-09-13)

• Primary citation: Aller, P.,Duclos, S.,Wallace, S.S.,Doublie, S.; A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex.; J.Mol.Biol., 412:22-34, 2011; PubMed: 21781974; DOI: 10.1016/j.jmb.2011.07.007

Experimental method

X-RAY DIFFRACTION (3 Å)