3QYY

A Novel Interaction Mode between a Microbial GGDEF Domain and the Bis-(3, 5 )-cyclic di-GMP

Summary for 3QYY

• Entry DOI: 10.2210/pdb3qyy/pdb
• Descriptor: Response regulator, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: c-di-gmp, dgc, ggdef, competitive inhibition, xanthomonas campestris, signaling protein-inhibitor complex, signaling protein/inhibitor
• Biological source: Xanthomonas campestris pv. campestris
• Total number of polymer chains: 2
• Total formula weight: 39264.07

Authors

Yang, C.-Y.,Chin, K.-H.,Chou, S.-H. (deposition date: 2011-03-04, release date: 2011-11-30, Last modification date: 2024-03-20)

• Primary citation: Yang, C.-Y.,Chin, K.-H.,Chuah, M.L.-C.,Liang, Z.-X.,Wang, A.H.-J.,Chou, S.-H.; The structure and inhibition of a GGDEF diguanylate cyclase complexed with (c-di-GMP)(2) at the active site; Acta Crystallogr.,Sect.D, 67:997-1008, 2011; PubMed: 22120736; DOI: 10.1107/S090744491104039X

Experimental method

X-RAY DIFFRACTION (1.9 Å)