3Q9A

Structure of neuronal nitric oxide synthase in the ferric state in complex with N-5-[2-(ethylsulfanyl)ethanimidoyl]-L-ornithine

Summary for 3Q9A

Entry DOI	10.2210/pdb3q9a/pdb
Related	3JT5 3Q99
Descriptor	Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
Functional Keywords	nitric oxide synthase, heme enzyme, oxidoreductase, inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Rattus norvegicus (Rat)
Cellular location	Cell membrane, sarcolemma ; Peripheral membrane protein : P29476
Total number of polymer chains	2
Total formula weight	99990.68
Authors	Li, H.,Doukov, T.,Poulos, T.L. (deposition date: 2011-01-07, release date: 2011-05-18, Last modification date: 2023-09-13)
Primary citation	Doukov, T.,Li, H.,Sharma, A.,Martell, J.D.,Soltis, S.M.,Silverman, R.B.,Poulos, T.L. Temperature-dependent spin crossover in neuronal nitric oxide synthase bound with the heme-coordinating thioether inhibitors. J.Am.Chem.Soc., 133:8326-8334, 2011 Cited by PubMed: 21534614 DOI: 10.1021/ja201466v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.24 Å)

Structure validation