3Q3G

Crystal Structure of A-domain in complex with antibody

Summary for 3Q3G

Entry DOI	10.2210/pdb3q3g/pdb
Descriptor	Antibody Light Chain, Antibody Heavy chain, Integrin alpha-M, ... (10 entities in total)
Functional Keywords	immune system-cell adhesion complex, immune system/cell adhesion
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P11215
Total number of polymer chains	12
Total formula weight	284196.39
Authors	Mahalingam, B.,Xiong, J.P.,Arnaout, M.A. (deposition date: 2010-12-21, release date: 2011-11-30, Last modification date: 2011-12-28)
Primary citation	Mahalingam, B.,Ajroud, K.,Alonso, J.L.,Anand, S.,Adair, B.D.,Horenstein, A.L.,Malavasi, F.,Xiong, J.P.,Arnaout, M.A. Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design. J.Immunol., 187:6393-6401, 2011 Cited by PubMed: 22095715 DOI: 10.4049/jimmunol.1102394 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation