3OQS

Crystal structure of importin-alpha bound to a CLIC4 NLS peptide

Summary for 3OQS

Entry DOI	10.2210/pdb3oqs/pdb
Descriptor	peptide of Chloride intracellular channel protein 4, Importin subunit alpha-2 (3 entities in total)
Functional Keywords	importin alpha, karyopherin alpha, nuclear localisation signal (nls) recognition, chloride intracellular channel 4, clic4 nls, armadillo repeat, nuclear import, protein transport
Biological source	Mus musculus (mouse) More
Cellular location	Cytoplasm, cytoskeleton, centrosome: Q9Y696 Cytoplasm (By similarity): P52293
Total number of polymer chains	2
Total formula weight	56539.06
Authors	Mynott, A.V.,Brown, L.J.,Harrop, S.J.,Curmi, P.M.G. (deposition date: 2010-09-03, release date: 2011-07-27, Last modification date: 2023-11-01)
Primary citation	Mynott, A.V.,Harrop, S.J.,Brown, L.J.,Breit, S.N.,Kobe, B.,Curmi, P.M.G. Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 Febs J., 278:1662-1675, 2011 Cited by PubMed: 21388519 DOI: 10.1111/j.1742-4658.2011.08086.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation