3OP0

Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide

Summary for 3OP0

• Entry DOI: 10.2210/pdb3op0/pdb
• Descriptor: Signal transduction protein CBL-C, Epidermal growth factor receptor, SODIUM ION, ... (5 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, signal transduction protein, sh3-binding protein, signaling protein-signaling protein regulator complex, signaling protein/signaling protein regulator
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533
• Total number of polymer chains: 4
• Total formula weight: 75084.49

Authors

Chaikuad, A.,Guo, K.,Cooper, C.D.O.,Ayinampudi, V.,Krojer, T.,Ugochukwu, E.,Muniz, J.R.C.,Vollmar, M.,Canning, P.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bountra, C.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2010-08-31, release date: 2010-10-20, Last modification date: 2023-12-06)

• Primary citation: Chaikuad, A.,Guo, K.,Cooper, C.D.O.,Ayinampudi, V.,Krojer, T.,Ugochukwu, E.,Muniz, J.R.C.,Vollmar, M.,Canning, P.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bountra, C.,Bullock, A.; Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide; To be Published,

Experimental method

X-RAY DIFFRACTION (2.52 Å)