3O65

Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity

Summary for 3O65

• Entry DOI: 10.2210/pdb3o65/pdb
• Descriptor: Putative ataxin-3-like protein, Ubiquitin, SODIUM ION, ... (4 entities in total)
• Functional Keywords: papain-like fold, ubiquitin thiolesterase, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q9H3M9; Ubiquitin: Cytoplasm : P0CG47
• Total number of polymer chains: 8
• Total formula weight: 123299.77

Authors

Weeks, S.D.,Grasty, K.C.,Hernandez-Cuebas, L.,Loll, P.J. (deposition date: 2010-07-28, release date: 2010-11-24, Last modification date: 2017-11-08)

• Primary citation: Weeks, S.D.,Grasty, K.C.,Hernandez-Cuebas, L.,Loll, P.J.; Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY.; J.Biol.Chem., 286:4555-4565, 2011; PubMed: 21118805; DOI: 10.1074/jbc.M110.177360

Experimental method

X-RAY DIFFRACTION (2.7 Å)