3O3R

Crystal Structure of AKR1B14 in complex with NADP

3O3R の概要

• エントリーDOI: 10.2210/pdb3o3r/pdb
• 分子名称: Aldo-keto reductase family 1, member B7, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• 機能のキーワード: aldose reductase like protein, akr1b14, oxidoreductase
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73834.33

構造登録者

Sundaram, K.,Dhagat, U.,El-Kabbani, O. (登録日: 2010-07-26, 公開日: 2011-01-19, 最終更新日: 2023-11-01)

• 主引用文献: Sundaram, K.,Dhagat, U.,Endo, S.,Chung, R.,Matsunaga, T.,Hara, A.,El-Kabbani, O.; Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis; Bioorg.Med.Chem.Lett., 21:801-804, 2011; PubMed: 21168333; DOI: 10.1016/j.bmcl.2010.11.086

実験手法

X-RAY DIFFRACTION (1.86 Å)