3NS6

Crystal structure of hte RNA recognition motif of yeast eIF3b residues 76-170

Summary for 3NS6

Entry DOI	10.2210/pdb3ns6/pdb
Related	3NS5
Descriptor	Eukaryotic translation initiation factor 3 subunit B, SULFATE ION (3 entities in total)
Functional Keywords	translation
Biological source	Saccharomyces cerevisiae (yeast)
Cellular location	Cytoplasm (Probable): P06103
Total number of polymer chains	2
Total formula weight	22544.12
Authors	Khoshnevis, S.,Neumann, P.,Ficner, R. (deposition date: 2010-07-01, release date: 2010-10-06, Last modification date: 2023-09-06)
Primary citation	Khoshnevis, S.,Neumann, P.,Ficner, R. Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b. Plos One, 5:e12784-e12784, 2010 Cited by PubMed Abstract: The multi-subunit eukaryotic initiation factor3 (eIF3) plays a central role in the initiation step of protein synthesis in eukaryotes. One of its large subunits, eIF3b, serves as a scaffold within eIF3 as it interacts with several other subunits. It harbors an RNA Recognition Motif (RRM), which is shown to be a non-canonical RRM in human as it is not capable to interact with oligonucleotides, but rather interacts with eIF3j, a sub-stoichiometric subunit of eIF3. PubMed: 20862284 DOI: 10.1371/journal.pone.0012784 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation