3NPW

In silico designed of an improved Kemp eliminase KE70 mutant by computational design and directed evolution

Summary for 3NPW

Entry DOI	10.2210/pdb3npw/pdb
Related	3NPU 3NPV 3NPX 3NQ2 3NQ8 3NQV 3NR0
Descriptor	deoxyribose phosphate aldolase (2 entities in total)
Functional Keywords	tim, structural genomics, israel structural proteomics center, ispc, lyase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	56025.91
Authors	Khersonsky, O.,Rothlisberge, D.,Wollacott, A.M.,Dym, O.,Baker, D.,Tawfik, D.S.,Israel Structural Proteomics Center (ISPC) (deposition date: 2010-06-29, release date: 2011-02-09, Last modification date: 2023-11-01)
Primary citation	Khersonsky, O.,Rothlisberger, D.,Wollacott, A.M.,Murphy, P.,Dym, O.,Albeck, S.,Kiss, G.,Houk, K.N.,Baker, D.,Tawfik, D.S. Optimization of the in-silico-designed kemp eliminase KE70 by computational design and directed evolution J.Mol.Biol., 407:391-412, 2011 Cited by PubMed: 21277311 DOI: 10.1016/j.jmb.2011.01.041 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.14 Å)

Structure validation