3MEA

Crystal structure of the SGF29 in complex with H3K4me3

Summary for 3MEA

Entry DOI	10.2210/pdb3mea/pdb
Related	3ME9 3MET 3MEU 3MEV 3MEW
Descriptor	SAGA-associated factor 29 homolog, Histone H3 (3 entities in total)
Functional Keywords	structural genomics consortium, sgc, nucleus, transcription, transcription regulation, chromosomal protein, dna-binding, nucleosome core
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : Q96ES7
Total number of polymer chains	2
Total formula weight	21735.43
Authors	Bian, C.,Xu, C.,Tempel, W.,MacKenzie, F.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2010-03-31, release date: 2010-04-28, Last modification date: 2023-09-06)
Primary citation	Bian, C.,Xu, C.,Ruan, J.,Lee, K.K.,Burke, T.L.,Tempel, W.,Barsyte, D.,Li, J.,Wu, M.,Zhou, B.O.,Fleharty, B.E.,Paulson, A.,Allali-Hassani, A.,Zhou, J.Q.,Mer, G.,Grant, P.A.,Workman, J.L.,Zang, J.,Min, J. Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30:2829-2842, 2011 Cited by PubMed: 21685874 DOI: 10.1038/emboj.2011.193 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.26 Å)

Structure validation