3MB8

Crystal structure of purine nucleoside phosphorylase from toxoplasma gondii in complex with immucillin-H

3MB8 の概要

• エントリーDOI: 10.2210/pdb3mb8/pdb
• 分子名称: Purine nucleoside phosphorylase, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: pnp, purine nucleoside phosphorylase, immucillin h, immh, transferase
• 由来する生物種: Toxoplasma gondii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 62258.84

構造登録者

Ho, M.,Almo, S.C.,Schramm, V.L. (登録日: 2010-03-25, 公開日: 2011-04-06, 最終更新日: 2024-05-22)

• 主引用文献: Donaldson, T.M.,Cassera, M.B.,Ho, M.C.,Zhan, C.,Merino, E.F.,Evans, G.B.,Tyler, P.C.,Almo, S.C.,Schramm, V.L.,Kim, K.; Inhibition and Structure of Toxoplasma gondii Purine Nucleoside Phosphorylase.; Eukaryot Cell, 13:572-579, 2014; PubMed: 24585883; DOI: 10.1128/EC.00308-13

実験手法

X-RAY DIFFRACTION (1.9 Å)