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3LRQ

Crystal structure of the U-box domain of human ubiquitin-protein ligase (E3), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4604D.

Summary for 3LRQ
Entry DOI10.2210/pdb3lrq/pdb
DescriptorE3 ubiquitin-protein ligase TRIM37, ZINC ION (3 entities in total)
Functional Keywordsstructural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, coiled coil, ligase, metal-binding, peroxisome, phosphoprotein, polymorphism, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total formula weight48753.10
Authors
Primary citationKuzin, A.,Chen, Y.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Shastry, R.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F.
E3 UBIQUITIN-PROTEIN LIGASE RING DOMAIN FROM HUMAN TRIPARTITE MOTIF-CONTAINING PROTEIN 37 (TRIM37), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4604D.
To be Published,
Experimental method
X-RAY DIFFRACTION (2.292 Å)
Structure validation

218500

數據於2024-04-17公開中

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