3LQJ

Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me3 peptide

Summary for 3LQJ

Entry DOI	10.2210/pdb3lqj/pdb
Related	3LQH 3LQI
Descriptor	MLL1 PHD3-Bromo, Histone H3, ZINC ION, ... (4 entities in total)
Functional Keywords	phd finger, bromodomain, mll1, leukemia, h3(1-9)k4me3, chromosomal protein, dna-binding, nucleosome core, nucleus, transferase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus . MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164 Nucleus: P68431
Total number of polymer chains	4
Total formula weight	45082.89
Authors	Wang, Z.,Patel, D.J. (deposition date: 2010-02-09, release date: 2010-07-07, Last modification date: 2017-07-26)
Primary citation	Wang, Z.,Song, J.,Milne, T.A.,Wang, G.G.,Li, H.,Allis, C.D.,Patel, D.J. Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141:1183-1194, 2010 Cited by PubMed: 20541251 DOI: 10.1016/j.cell.2010.05.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation