3LOJ
Structure of Mycobacterium tuberculosis dUTPase H145A mutant
Summary for 3LOJ
Entry DOI | 10.2210/pdb3loj/pdb |
Related | 3HZA |
Descriptor | Deoxyuridine 5'-triphosphate nucleotidohydrolase, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, GLYCEROL, ... (7 entities in total) |
Functional Keywords | hydrolase, jelly roll, domain swapping, nucleotide metabolism, magnesium, metal-binding |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 18777.98 |
Authors | Leveles, I.,Harmat, V.,Pecsi, I.,Lopata, A.,Vertessy, B.G.,Toth, J. (deposition date: 2010-02-04, release date: 2010-08-11, Last modification date: 2023-11-01) |
Primary citation | Pecsi, I.,Leveles, I.,Harmat, V.,Vertessy, B.G.,Toth, J. Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase Nucleic Acids Res., 38:7179-7186, 2010 Cited by PubMed: 20601405DOI: 10.1093/nar/gkq584 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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