3LKZ

Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase

Summary for 3LKZ

• Entry DOI: 10.2210/pdb3lkz/pdb
• Related: 2OY0
• Descriptor: Non-structural protein 5, SINEFUNGIN, GLYCEROL, ... (4 entities in total)
• Functional Keywords: west nile virus, flavivirus, methyltransferase, inhibitor, pocket, nucleotide-binding, rna replication, viral protein
• Biological source: West Nile virus (WNV)
• Cellular location: Envelope protein E: Virion membrane; Multi- pass membrane protein: Q9Q6P4
• Total number of polymer chains: 2
• Total formula weight: 74432.59

Authors

Liu, L.H.,Li, H.M. (deposition date: 2010-01-28, release date: 2010-08-04, Last modification date: 2023-09-06)

• Primary citation: Dong, H.,Liu, L.,Zou, G.,Zhao, Y.,Li, Z.,Lim, S.P.,Shi, P.Y.,Li, H.; Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase.; J.Biol.Chem., 285:32586-32595, 2010; PubMed: 20685660; DOI: 10.1074/jbc.M110.129197

Experimental method

X-RAY DIFFRACTION (2 Å)