3LHP

Crystal structure of HIV epitope-scaffold 4E10_D0_1ISEA_004_N 4E10 Fv complex

Summary for 3LHP

• Entry DOI: 10.2210/pdb3lhp/pdb
• Related: 3LEF 3LF6 3LG7 3LH2 3LHP
• Descriptor: Fv 4E10 heavy chain, Fv 4E10 light chain, 4E10_D0_1ISEA_004_N (T93), ... (5 entities in total)
• Functional Keywords: epitope-scaffold, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 82202.39

Authors

Holmes, M.A. (deposition date: 2010-01-22, release date: 2010-09-22, Last modification date: 2023-09-06)

• Primary citation: Correia, B.E.,Ban, Y.E.,Holmes, M.A.,Xu, H.,Ellingson, K.,Kraft, Z.,Carrico, C.,Boni, E.,Sather, D.N.,Zenobia, C.,Burke, K.Y.,Bradley-Hewitt, T.,Bruhn-Johannsen, J.F.,Kalyuzhniy, O.,Baker, D.,Strong, R.K.,Stamatatos, L.,Schief, W.R.; Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.; Structure, 18:1116-1126, 2010; PubMed: 20826338; DOI: 10.1016/j.str.2010.06.010

Experimental method

X-RAY DIFFRACTION (2.7 Å)