3L5N

Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b

3L5N の概要

• エントリーDOI: 10.2210/pdb3l5n/pdb
• 関連するPDBエントリー: 3L3O
• 分子名称: Complement C3, Staphylococcal complement inhibitor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: complement alternate pathway, complement pathway, converstase, immune response, inflammatory response, innate immunity, secreted, virulence, immune evasion, immune system
• 由来する生物種: Staphylococcus aureus; 詳細
• 細胞内の位置: Secreted: P01024 P01024 Q931M7
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 186374.63

構造登録者

Geisbrecht, B.V.,Garcia, B.L. (登録日: 2009-12-22, 公開日: 2010-08-04, 最終更新日: 2023-09-06)

• 主引用文献: Garcia, B.L.,Ramyar, K.X.,Tzekou, A.,Ricklin, D.,McWhorter, W.J.,Lambris, J.D.,Geisbrecht, B.V.; Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.; J.Mol.Biol., 402:17-29, 2010; PubMed: 20654625; DOI: 10.1016/j.jmb.2010.07.029

実験手法

X-RAY DIFFRACTION (7.536 Å)