3KOH
Cytochrome P450 2E1 with omega-imidazolyl octanoic acid
Summary for 3KOH
Entry DOI | 10.2210/pdb3koh/pdb |
Related | 3E4E 3E6I 3GPH |
Descriptor | Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE, 8-(1H-imidazol-1-yl)octanoic acid, ... (4 entities in total) |
Functional Keywords | cyp2e1, p450 2e1, monooxygenase, heme, fatty acid, microsome, membrane, oxidoreductase, endoplasmic reticulum, iron, metal-binding |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P05181 |
Total number of polymer chains | 2 |
Total formula weight | 111770.50 |
Authors | Scott, E.E.,Porubsky, P.R. (deposition date: 2009-11-13, release date: 2010-05-12, Last modification date: 2023-09-06) |
Primary citation | Porubsky, P.R.,Battaile, K.P.,Scott, E.E. Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode. J.Biol.Chem., 285:22282-22290, 2010 Cited by PubMed: 20463018DOI: 10.1074/jbc.M110.109017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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