Structure of the idle mammalian ribosome-Sec61 complex

This is a large structure.
Replaces:  3J72

Summary for 3J7Q

Related3J7O 3J7P 3J7R
Integrates4W24 4W25
EMDB information2644 2646 2649 2650
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (50 entities in total)
Functional Keywordsmammalian, sec61, translocation, translation, ribosome
Biological sourceSus scrofa (Pig)
Total number of polymer chains48
Total molecular weight2172228.42
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.W.,Hegde, R.S. (deposition date: 2014-08-01, release date: 2014-09-03, Last modification date: 2019-10-30)
Primary citation
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.,Hegde, R.S.
Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157:1632-1643, 2014
PubMed: 24930395 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2014.05.024
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone56 4.2% 20.9% 0.28MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report