3J7E

Electron cryo-microscopy of human papillomavirus 16 and H16.V5 Fab fragments

Summary for 3J7E

• Entry DOI: 10.2210/pdb3j7e/pdb
• Related: 3J7G
• EMDB information: 5991 5992 5993 5994
• Descriptor: H16.V5 Fab light chain, H16.V5 Fab heavy chain (2 entities in total)
• Functional Keywords: hpv16.v5 fab variable domain, hi and fg loops, hpv16 capsid, virus-fab complex, neutralization antibody, maturation, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 8
• Total formula weight: 104484.52

Authors

Lee, H.,Brendle, S.A.,Bywaters, S.M.,Christensen, N.D.,Hafenstein, S. (deposition date: 2014-06-23, release date: 2014-11-26, Last modification date: 2018-07-18)

• Primary citation: Lee, H.,Brendle, S.A.,Bywaters, S.M.,Guan, J.,Ashley, R.E.,Yoder, J.D.,Makhov, A.M.,Conway, J.F.,Christensen, N.D.,Hafenstein, S.; A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment.; J.Virol., 89:1428-1438, 2015; PubMed: 25392224; DOI: 10.1128/JVI.02898-14

Experimental method

ELECTRON MICROSCOPY (13.6 Å)