3INA

Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin

Summary for 3INA

Entry DOI	10.2210/pdb3ina/pdb
Related	3IMN 3IN9
Descriptor	Heparin lyase I, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, ... (4 entities in total)
Functional Keywords	jelly roll, lyase
Biological source	Bacteroides thetaiotaomicron
Total number of polymer chains	1
Total formula weight	45215.33
Authors	Han, Y.H.,Ryu, K.S.,Kim, H.Y.,Jeon, Y.H. (deposition date: 2009-08-12, release date: 2009-09-29, Last modification date: 2023-11-01)
Primary citation	Han, Y.H.,Garron, M.L.,Kim, H.Y.,Kim, W.S.,Zhang, Z.,Ryu, K.S.,Shaya, D.,Xiao, Z.,Cheong, C.,Kim, Y.S.,Linhardt, R.J.,Jeon, Y.H.,Cygler, M. Structural snapshots of heparin depolymerization by heparin lyase I J.Biol.Chem., 284:34019-34027, 2009 Cited by PubMed: 19801541 DOI: 10.1074/jbc.M109.025338 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation