3INA

Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin

3INA の概要

• エントリーDOI: 10.2210/pdb3ina/pdb
• 関連するPDBエントリー: 3IMN 3IN9
• 分子名称: Heparin lyase I, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: jelly roll, lyase
• 由来する生物種: Bacteroides thetaiotaomicron
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45215.33

構造登録者

Han, Y.H.,Ryu, K.S.,Kim, H.Y.,Jeon, Y.H. (登録日: 2009-08-12, 公開日: 2009-09-29, 最終更新日: 2023-11-01)

• 主引用文献: Han, Y.H.,Garron, M.L.,Kim, H.Y.,Kim, W.S.,Zhang, Z.,Ryu, K.S.,Shaya, D.,Xiao, Z.,Cheong, C.,Kim, Y.S.,Linhardt, R.J.,Jeon, Y.H.,Cygler, M.; Structural snapshots of heparin depolymerization by heparin lyase I; J.Biol.Chem., 284:34019-34027, 2009; PubMed: 19801541; DOI: 10.1074/jbc.M109.025338

実験手法

X-RAY DIFFRACTION (1.9 Å)