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3IFN

X-ray structure of amyloid beta peptide:antibody (Abeta1-40:12A11) complex

Summary for 3IFN
Entry DOI10.2210/pdb3ifn/pdb
Related3IFL 3IFO 3IFP
Descriptor12A11 FAB antibody heavy chain, 12A11 FAB antibody light chain, Amyloid beta A4 protein, ... (4 entities in total)
Functional Keywordsantibody, amyloid beta peptide, immune system
Biological sourceMus musculus (mouse)
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Cellular locationMembrane; Single-pass type I membrane protein: 3IFN
Total number of polymer chains3
Total formula weight52405.49
Authors
Weis, W.I.,Feinberg, H.,Basi, G.S.,Schenk, D. (deposition date: 2009-07-24, release date: 2009-11-17, Last modification date: 2013-06-19)
Primary citationBasi, G.S.,Feinberg, H.,Oshidari, F.,Anderson, J.,Barbour, R.,Baker, J.,Comery, T.A.,Diep, L.,Gill, D.,Johnson-Wood, K.,Goel, A.,Grantcharova, K.,Lee, M.,Li, J.,Partridge, A.,Griswold-Prenner, I.,Piot, N.,Walker, D.,Widom, A.,Pangalos, M.N.,Seubert, P.,Jacobsen, J.S.,Schenk, D.,Weis, W.I.
Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285:3417-3427, 2010
Cited by
PubMed: 19923222
DOI: 10.1074/jbc.M109.045187
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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