3HZA

Crystal structure of dUTPase H145W mutant

Summary for 3HZA

Entry DOI	10.2210/pdb3hza/pdb
Descriptor	Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	jelly roll, domain swapping, hydrolase, nucleotide metabolism
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	18838.17
Authors	Leveles, I.,Harmat, V.,Pecsi, I.,Toth, J.,Vertessy, B.G. (deposition date: 2009-06-23, release date: 2009-11-24, Last modification date: 2023-09-06)
Primary citation	Pecsi, I.,Leveles, I.,Harmat, V.,Vertessy, B.G.,Toth, J. Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase. Nucleic Acids Res., 38:7179-7186, 2010 Cited by PubMed: 20601405 DOI: 10.1093/nar/gkq584 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation