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3HXI

Crystal structure of Schistosome eIF4E complexed with m7GpppG and 4E-BP

Summary for 3HXI
Entry DOI10.2210/pdb3hxi/pdb
Related3HXG
DescriptorEukaryotic Translation Initiation 4E, Eukaryotic translation initiation factor 4E-binding protein 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ... (4 entities in total)
Functional Keywordsprotein-mrna cap complex, acetylation, phosphoprotein, protein synthesis inhibitor, translation regulation, translation
Biological sourceSchistosoma mansoni
More
Total number of polymer chains2
Total formula weight25474.09
Authors
Liu, W.,Zhao, R.,Jones, D.N.M.,Davis, R.E. (deposition date: 2009-06-20, release date: 2009-08-25, Last modification date: 2023-09-06)
Primary citationLiu, W.,Zhao, R.,McFarland, C.,Kieft, J.,Niedzwiecka, A.,Jankowska-Anyszka, M.,Stepinski, J.,Darzynkiewicz, E.,Jones, D.N.,Davis, R.E.
Structural insights into parasite EIF4E binding specificity for m7G and m2,2,7G mRNA cap.
J.Biol.Chem., 284:31336-31349, 2009
Cited by
PubMed: 19710013
DOI: 10.1074/jbc.M109.049858
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

数据于2024-03-27公开中

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