3HTM

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPBTB/3-box

Summary for 3HTM

Entry DOI	10.2210/pdb3htm/pdb
Related	3HQI 3HQL 3HQM 3HSV 3HU6 3HVE
Descriptor	Speckle-type POZ protein (2 entities in total)
Functional Keywords	btb, spop, ubiquitin, ligase, nucleus, ubl conjugation pathway, protein binding
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O43791
Total number of polymer chains	4
Total formula weight	77182.50
Authors	Zhuang, M.,Walden, H.,Schulman, B.A. (deposition date: 2009-06-11, release date: 2009-10-20, Last modification date: 2011-07-13)
Primary citation	Zhuang, M.,Calabrese, M.F.,Liu, J.,Waddell, M.B.,Nourse, A.,Hammel, M.,Miller, D.J.,Walden, H.,Duda, D.M.,Seyedin, S.N.,Hoggard, T.,Harper, J.W.,White, K.P.,Schulman, B.A. Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol.Cell, 36:39-50, 2009 Cited by PubMed: 19818708 DOI: 10.1016/j.molcel.2009.09.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation