3HQD

Human kinesin Eg5 motor domain in complex with AMPPNP and Mg2+

3HQD の概要

• エントリーDOI: 10.2210/pdb3hqd/pdb
• 関連するPDBエントリー: 1ii6 1q0b 1x88 2ieh
• 分子名称: Kinesin-like protein KIF11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: kinesin, motor domain, atp hydrolysis, mitosis, spindle protein, atp-binding, cell cycle, cell division, coiled coil, microtubule, motor protein, nucleotide-binding, phosphoprotein, polymorphism
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P52732
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 83493.45

構造登録者

Parke, C.L.,Wojcik, E.J.,Kim, S.,Worthylake, D.K. (登録日: 2009-06-05, 公開日: 2009-12-08, 最終更新日: 2023-09-06)

• 主引用文献: Parke, C.L.,Wojcik, E.J.,Kim, S.,Worthylake, D.K.; ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism.; J.Biol.Chem., 285:5859-5867, 2010; PubMed: 20018897; DOI: 10.1074/jbc.M109.071233

実験手法

X-RAY DIFFRACTION (2.19 Å)