3HPN
Ligand recognition by A-class EPH receptors: crystal structures of the EPHA2 ligand-binding domain and the EPHA2/EPHRIN-A1 complex
Summary for 3HPN
Entry DOI | 10.2210/pdb3hpn/pdb |
Descriptor | Ephrin type-A receptor 2 (2 entities in total) |
Functional Keywords | eph receptor tyrosine kinase, ephrin, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, transferase, transmembrane, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P29317 |
Total number of polymer chains | 6 |
Total formula weight | 119481.55 |
Authors | Himanen, J.P.,Goldgur, Y.,Miao, H.,Myshkin, E.,Guo, H.,Buck, M.,Nguyen, M.,Rajashankar, K.R.,Wang, B.,Nikolov, D.B. (deposition date: 2009-06-04, release date: 2009-06-30, Last modification date: 2023-09-06) |
Primary citation | Himanen, J.P.,Goldgur, Y.,Miao, H.,Myshkin, E.,Guo, H.,Buck, M.,Nguyen, M.,Rajashankar, K.R.,Wang, B.,Nikolov, D.B. Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. Embo Rep., 10:722-728, 2009 Cited by PubMed: 19525919DOI: 10.1038/embor.2009.91 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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