3HCV
Crystal structure of HLA-B*2709 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)
3HCV の概要
エントリーDOI | 10.2210/pdb3hcv/pdb |
関連するPDBエントリー | 1of2 1ogt 3b3i 3b6s |
分子名称 | HLA class I histocompatibility antigen, B-27 alpha chain, Beta-2-microglobulin, DOUBLE CITRULLINATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR, ... (4 entities in total) |
機能のキーワード | immune system-complex, mhc (major histocompatibility complex) i, hla-b*2709, glycoprotein, host-virus, immune response, polymorphism, immunoglobulin domain, host-virus interaction, membrane, transmembrane, ubl conjugation, disease mutation, glycation, pyrrolidone carboxylic acid, secreted, disulfide bond, mhc i, immune system |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Membrane; Single-pass type I membrane protein: P03989 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 45230.22 |
構造登録者 | Beltrami, A.,Gabdulkhakov, A.,Rossmann, M.,Ziegler, A.,Uchanska-Ziegler, B.,Saenger, W. (登録日: 2009-05-06, 公開日: 2009-06-09, 最終更新日: 2023-11-15) |
主引用文献 | Beltrami, A.,Rossmann, M.,Gabdulkhakov, A.,Ziegler, A.,Uchanska-Ziegler, B.,Saenger, W. Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide To be Published, |
実験手法 | X-RAY DIFFRACTION (1.95 Å) |
構造検証レポート
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