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3H8K

Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution

Summary for 3H8K
Entry DOI10.2210/pdb3h8k/pdb
Related2CYX 3FSH
DescriptorUbiquitin-conjugating enzyme E2 G2, Autocrine motility factor receptor, isoform 2 (3 entities in total)
Functional Keywordsalpha beta, all alpha, ligase, ubl conjugation pathway, endoplasmic reticulum, membrane, metal-binding, phosphoprotein, receptor, transmembrane, zinc-finger
Biological sourceHomo sapiens (human)
More
Cellular locationEndoplasmic reticulum membrane ; Multi-pass membrane protein : Q9UKV5
Total number of polymer chains2
Total formula weight22003.18
Authors
Kalathur, R.C.,Das, R.,Li, J.,Byrd, R.A.,Ji, X. (deposition date: 2009-04-29, release date: 2009-07-14, Last modification date: 2023-09-06)
Primary citationDas, R.,Mariano, J.,Tsai, Y.C.,Kalathur, R.C.,Kostova, Z.,Li, J.,Tarasov, S.G.,McFeeters, R.L.,Altieri, A.S.,Ji, X.,Byrd, R.A.,Weissman, A.M.
Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
Mol.Cell, 34:674-685, 2009
Cited by
PubMed: 19560420
DOI: 10.1016/j.molcel.2009.05.010
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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