3H6D

Structure of the mycobacterium tuberculosis DUTPase D28N mutant

Summary for 3H6D

Entry DOI	10.2210/pdb3h6d/pdb
Descriptor	Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	jelly-roll, hydrolase, nucleotide metabolism
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	18727.08
Authors	Leveles, I.,Harmat, V.,Nagy, G.,Takacs, E.,Lopata, A.,Toth, J.,Vertessy, B.G. (deposition date: 2009-04-23, release date: 2009-11-24, Last modification date: 2023-09-06)
Primary citation	Takacs, E.,Nagy, G.,Leveles, I.,Harmat, V.,Lopata, A.,Toth, J.,Vertessy, B.G. Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases. Febs Lett., 584:3047-3054, 2010 Cited by PubMed: 20493855 DOI: 10.1016/j.febslet.2010.05.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation