3GSO

Crystal structure of the binary complex between HLA-A2 and HCMV NLV peptide

Summary for 3GSO

• Entry DOI: 10.2210/pdb3gso/pdb
• Related: 3GSN 3GSQ 3GSR 3GSU 3GSV 3GSW 3GSX
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, HCMV pp65 fragment 495-503 (NLVPMVATV), ... (4 entities in total)
• Functional Keywords: hla, human cytomegalovirus, pp65, t cell receptor (tcr), immune response, public response, immunodominance, restrained response, host-virus interaction, membrane, mhc i, polymorphism, immunoglobulin domain, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 3
• Total formula weight: 44575.66

Authors

Gras, S.,Saulquin, X.,Reiser, J.-B.,Debeaupuis, E.,Echasserieau, K.,Kissenpfennig, A.,Legoux, F.,Chouquet, A.,Le Gorrec, M.,Machillot, P.,Neveu, B.,Thielens, N.,Malissen, B.,Bonneville, M.,Housset, D. (deposition date: 2009-03-27, release date: 2009-08-04, Last modification date: 2021-10-20)

• Primary citation: Gras, S.,Saulquin, X.,Reiser, J.B.,Debeaupuis, E.,Echasserieau, K.,Kissenpfennig, A.,Legoux, F.,Chouquet, A.,Le Gorrec, M.,Machillot, P.,Neveu, B.,Thielens, N.,Malissen, B.,Bonneville, M.,Housset, D.; Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.; J.Immunol., 183:430-437, 2009; PubMed: 19542454; DOI: 10.4049/jimmunol.0900556

Experimental method

X-RAY DIFFRACTION (1.6 Å)