3G2G

S437Y Mutant of human muscle pyruvate kinase, isoform M2

3G2G の概要

• エントリーDOI: 10.2210/pdb3g2g/pdb
• 分子名称: Pyruvate kinase isozymes M1/M2, SULFATE ION, UNKNOWN ATOM OR ION, ... (4 entities in total)
• 機能のキーワード: structural genomics consortium (sgc), single nucleotide polymorphism, snp, mutation, acetylation, allosteric enzyme, alternative splicing, glycolysis, kinase, magnesium, metal-binding, phosphoprotein, polymorphism, pyruvate, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm : P14618
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 234197.16

構造登録者

Hong, B.,Dimov, S.,Allali-Hassani, A.,Tempel, W.,MacKenzie, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, c.,Weigelt, J.,Bochkarev, A.,Vedadi, M.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2009-01-31, 公開日: 2009-03-03, 最終更新日: 2023-09-06)

• 主引用文献: Allali-Hassani, A.,Hong, B.,Dimov, S.,Tempel, W.,MacKenzie, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, c.,Weigelt, J.,Bochkarev, A.,Park, H.,Vedadi, M.; S437Y Mutant of human muscle pyruvate kinase, isoform M2; To be Published,

実験手法

X-RAY DIFFRACTION (2 Å)