3FVO

Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with 8-epi-neodysiherbaine A in space group P1

Summary for 3FVO

• Entry DOI: 10.2210/pdb3fvo/pdb
• Related: 2ZNS 2ZNT 2ZNU 3FUZ 3FV1 3FV2 3FVG 3FVK 3FVN
• Descriptor: Glutamate receptor, ionotropic kainate 1, GLYCEROL, (2R,3aR,6R,7S,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-6,7-dihydroxy-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid, ... (5 entities in total)
• Functional Keywords: glutamate receptor, ligand-binding domain, 8-epi-neodysiherbaine, membrane protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P39086
• Total number of polymer chains: 2
• Total formula weight: 60074.58

Authors

Unno, M.,Sasaki, M.,Ikeda-Saito, M. (deposition date: 2009-01-16, release date: 2010-01-19, Last modification date: 2023-11-01)

• Primary citation: Unno, M.,Shinohara, M.,Takayama, K.,Teruya, K.,Doh-ura, K.,Sakai, R.,Sasaki, M.,Ikeda-Saito, M.; Crystal Structures of Human GluR5 Ligand-Binding Core in Complexes with Novel Marine-Derived Toxins, Dysiherbaine and Neodysiherbaine A, and Their Analogues; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)