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3FJN

The crystal structure of 17-alpha hydroxysteroid dehydrogenase Y224D mutant.

Summary for 3FJN
Entry DOI10.2210/pdb3fjn/pdb
DescriptorAldo-keto reductase family 1 member C21, ACETATE ION (3 entities in total)
Functional Keywordsaldo-keto reductase, 17-alpha-hydroxysteroid dehydrogenase, cytoplasm, lipid metabolism, nadp, oxidoreductase, phosphoprotein, steroid metabolism
Biological sourceMus musculus (mouse)
Cellular locationCytoplasm (By similarity): Q91WR5
Total number of polymer chains2
Total formula weight73989.16
Authors
Dhagat, U.,El-Kabbani, O. (deposition date: 2008-12-14, release date: 2009-11-24, Last modification date: 2023-11-01)
Primary citationDhagat, U.,Endo, S.,Mamiya, H.,Hara, A.,El-Kabbani, O.
Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme
Acta Crystallogr.,Sect.D, 66:198-204, 2010
Cited by
PubMed: 20124700
DOI: 10.1107/S0907444909051464
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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