3FGS

Crystal structure of G65R/K206E double mutant of the N-lobe human transferrin

Summary for 3FGS

Entry DOI	10.2210/pdb3fgs/pdb
Related	1a8e 2O84
Descriptor	Serotransferrin, CARBONATE ION, FE (III) ION, ... (4 entities in total)
Functional Keywords	human transferrin, iron binding protein, dilysine pair, disease mutation, glycoprotein, ion transport, iron, iron transport, metal-binding, methylation, phosphoprotein, polymorphism, secreted, transport, metal transport
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02787
Total number of polymer chains	1
Total formula weight	37431.20
Authors	Halbrooks, P.J.,Mason, A.B.,Everse, S.J. (deposition date: 2008-12-08, release date: 2009-05-19, Last modification date: 2021-10-20)
Primary citation	Mason, A.B.,Halbrooks, P.J.,James, N.G.,Byrne, S.L.,Grady, J.K.,Chasteen, N.D.,Bobst, C.E.,Kaltashov, I.A.,Smith, V.C.,Macgillivray, R.T.,Everse, S.J. Structural and Functional Consequences of the Substitution of Glycine 65 with Arginine in the N-Lobe of Human Transferrin. Biochemistry, 48:1945-1953, 2009 Cited by PubMed: 19219998 DOI: 10.1021/bi802254x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation