3F6Q

Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain

Summary for 3F6Q

• Entry DOI: 10.2210/pdb3f6q/pdb
• Descriptor: Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, IODIDE ION, ... (6 entities in total)
• Functional Keywords: ilk, integrin-linked kinase, pinch, lim, ankyrin repeat, ank, ipp, integrin-mediated signaling, ank repeat, atp-binding, cell junction, cell membrane, kinase, membrane, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, acetylation, lim domain, metal-binding, zinc, transferase-metal binding protein complex, signaling protein-signaling protein complex, signaling protein/signaling protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell junction, focal adhesion: Q13418 P48059
• Total number of polymer chains: 2
• Total formula weight: 31055.14

Authors

Chiswell, B.P.,Calderwood, D.A.,Boggon, T.J. (deposition date: 2008-11-06, release date: 2008-12-02, Last modification date: 2023-09-06)

• Primary citation: Chiswell, B.P.,Zhang, R.,Murphy, J.W.,Boggon, T.J.,Calderwood, D.A.; The structural basis of integrin-linked kinase-PINCH interactions.; Proc.Natl.Acad.Sci.USA, 105:20677-20682, 2008; PubMed: 19074270; DOI: 10.1073/pnas.0811415106

Experimental method

X-RAY DIFFRACTION (1.6 Å)