Crystal Structure of Human IL-18 in complex with Ectromelia virus IL-18 Binding Protein

Summary for 3F62

DescriptorInterleukin 18 binding protein, Interleukin-18 (3 entities in total)
Functional Keywordsimmunoglobulin, il-18, beta trefoil, cytokine, secreted
Biological sourceEctromelia virus
Cellular locationSecreted Q14116
Total number of polymer chains2
Total molecular weight30600.54
Krumm, B.E.,Li, Y.,Deng, J. (deposition date: 2008-11-05, release date: 2009-01-06, Last modification date: 2011-07-13)
Primary citation
Krumm, B.,Meng, X.,Li, Y.,Xiang, Y.,Deng, J.
Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein.
Proc.Natl.Acad.Sci.USA, 105:20711-20715, 2008
PubMed: 19104048 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0809086106
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.253301.7%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution