3EKZ

Structural Characterization of tetrameric Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase - substrate binding and catalysis mechanism of a class IIa bacterial aldolase

3EKZ の概要

• エントリーDOI: 10.2210/pdb3ekz/pdb
• 関連するPDBエントリー: 3EKL 3ELF
• 分子名称: Fructose-bisphosphate aldolase, 1,3-DIHYDROXYACETONEPHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, ... (6 entities in total)
• 機能のキーワード: class ii fructose-1, 6-bisphosphate aldolase, zinc enzyme, mycobacterium tuberculosis, dihydroxyacetone, glyceraldehyde-3-phosphate, aldol condensation, glycolysis, lyase, metal-binding, zinc
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37942.10

構造登録者

Pegan, S.,Rukseree, K.,Franzblau, S.G.,Mesecar, A.D. (登録日: 2008-09-19, 公開日: 2009-02-10, 最終更新日: 2023-08-30)

• 主引用文献: Pegan, S.D.,Rukseree, K.,Franzblau, S.G.,Mesecar, A.D.; Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis; J.Mol.Biol., 386:1038-1053, 2009; PubMed: 19167403; DOI: 10.1016/j.jmb.2009.01.003

実験手法

X-RAY DIFFRACTION (2.07 Å)