3EJG

Crystal structure of HCoV-229E X-domain

Summary for 3EJG

• Entry DOI: 10.2210/pdb3ejg/pdb
• Related: 3EJF 3EJG
• Descriptor: Non-structural protein 3 (2 entities in total)
• Functional Keywords: hcov 229e, human coronavirus, x-domain, macro domain, nsp3, adrp, hydrolase, ribosomal frameshifting, rna-binding
• Biological source: Human coronavirus 229E (HCoV-229E)
• Cellular location: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6X1
• Total number of polymer chains: 1
• Total formula weight: 21343.43

Authors

Piotrowski, Y.,Hansen, G.,Hilgenfeld, R. (deposition date: 2008-09-18, release date: 2008-09-30, Last modification date: 2024-02-21)

• Primary citation: Piotrowski, Y.,Hansen, G.,Boomaars-van der Zanden, A.L.,Snijder, E.J.,Gorbalenya, A.E.,Hilgenfeld, R.; Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property.; Protein Sci., 18:6-16, 2009; PubMed: 19177346; DOI: 10.1002/pro.15

Experimental method

X-RAY DIFFRACTION (1.78 Å)