3DZG

Crystal structure of human CD38 extracellular domain, ara-F-ribose-5'-phosphate/nicotinamide complex

Summary for 3DZG

Entry DOI	10.2210/pdb3dzg/pdb
Related	3DZF 3DZH 3DZI 3DZJ 3DZK
Descriptor	ADP-ribosyl cyclase 1, 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-arabinofuranose, NICOTINAMIDE, ... (4 entities in total)
Functional Keywords	covalent intermediate complex, nicotinamide complex, beta sheets, alpha bundle, diabetes mellitus, glycoprotein, hydrolase, membrane, nad, receptor, signal-anchor, transmembrane
Biological source	Homo sapiens
Total number of polymer chains	2
Total formula weight	61469.24
Authors	Liu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q. (deposition date: 2008-07-29, release date: 2008-11-04, Last modification date: 2023-08-30)
Primary citation	Liu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q. Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38. Chem.Biol., 15:1068-1078, 2008 Cited by PubMed: 18940667 DOI: 10.1016/j.chembiol.2008.08.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation