3DQV
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation
Summary for 3DQV
Entry DOI | 10.2210/pdb3dqv/pdb |
Descriptor | NEDD8, Cullin-5, Rbx1, ... (4 entities in total) |
Functional Keywords | ubiquitin, nedd8, scf, cullin-ring ligase, cullin, nucleus, ubl conjugation pathway, host-virus interaction, receptor, ubl conjugation, acetylation, cytoplasm, dna damage, dna repair, metal-binding, zinc, zinc-finger, signaling protein, ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q15843 Cytoplasm: P62877 |
Total number of polymer chains | 6 |
Total formula weight | 134119.07 |
Authors | Duda, D.M.,Borg, L.A.,Scott, D.C.,Hunt, H.W.,Hammel, M.,Schulman, B.A. (deposition date: 2008-07-09, release date: 2008-09-30, Last modification date: 2011-07-13) |
Primary citation | Duda, D.M.,Borg, L.A.,Scott, D.C.,Hunt, H.W.,Hammel, M.,Schulman, B.A. Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134:995-1006, 2008 Cited by PubMed: 18805092DOI: 10.1016/j.cell.2008.07.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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