3DPL

Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation.

Summary for 3DPL

Entry DOI	10.2210/pdb3dpl/pdb
Descriptor	Cullin-5, RING-box protein 1, ZINC ION, ... (4 entities in total)
Functional Keywords	ubiquitin, nedd8, cullin, host-virus interaction, receptor, ubl conjugation, ubl conjugation pathway, acetylation, cytoplasm, dna damage, dna repair, metal-binding, nucleus, zinc, zinc-finger, ligase
Biological source	Homo sapiens More
Cellular location	Cytoplasm: P62877
Total number of polymer chains	2
Total formula weight	57278.10
Authors	Duda, D.M.,Schulman, B.A. (deposition date: 2008-07-08, release date: 2008-09-30, Last modification date: 2021-10-20)
Primary citation	Duda, D.M.,Borg, L.A.,Scott, D.C.,Hunt, H.W.,Hammel, M.,Schulman, B.A. Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134:995-1006, 2008 Cited by PubMed: 18805092 DOI: 10.1016/j.cell.2008.07.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation