3DKB

Crystal Structure of A20, 2.5 angstrom

Summary for 3DKB

• Entry DOI: 10.2210/pdb3dkb/pdb
• Descriptor: Tumor necrosis factor, alpha-induced protein 3 (1 entity in total)
• Functional Keywords: otu domain, dub domain, apoptosis, cytoplasm, dna-binding, hydrolase, metal-binding, nucleus, phosphoprotein, polymorphism, protease, thiol protease, ubl conjugation pathway, zinc, zinc-finger
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm. A20p50: Cytoplasm: P21580
• Total number of polymer chains: 6
• Total formula weight: 274015.38

Authors

Lin, S.-C.,Chung, J.Y.,Lo, Y.-C.,Wu, H. (deposition date: 2008-06-24, release date: 2008-07-08, Last modification date: 2024-02-21)

• Primary citation: Lin, S.-C.,Chung, J.Y.,Lamothe, B.,Rajashankar, K.,Lu, M.,Lo, Y.-C.,Lam, A.Y.,Darnay, B.G.,Wu, H.; Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20; J.Mol.Biol., 376:526-540, 2008; PubMed: 18164316; DOI: 10.1016/j.jmb.2007.11.092

Experimental method

X-RAY DIFFRACTION (2.5 Å)