3CCO
Structural adaptation and conservation in quadruplex-drug recognition
Summary for 3CCO
| Entry DOI | 10.2210/pdb3cco/pdb |
| Related | 3CDM |
| Descriptor | DNA (5'-D(*DTP*DAP*DGP*DGP*DGP*DTP*DTP*DAP*DGP*DGP*DGP*DT)-3'), SODIUM ION, POTASSIUM ION, ... (5 entities in total) |
| Functional Keywords | quadruplex, dna, propeller, dimeric, human telomere parallel stranded, ligand, complex, naphthalene diimidine |
| Total number of polymer chains | 1 |
| Total formula weight | 5661.82 |
| Authors | Parkinson, G.N.,Neidle, S. (deposition date: 2008-02-26, release date: 2008-09-23, Last modification date: 2023-11-01) |
| Primary citation | Parkinson, G.N.,Cuenca, F.,Neidle, S. Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes J.Mol.Biol., 381:1145-1156, 2008 Cited by PubMed: 18619463DOI: 10.1016/j.jmb.2008.06.022 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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