3BXN

The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA

Summary for 3BXN

• Entry DOI: 10.2210/pdb3bxn/pdb
• Related: 3BVN
• Descriptor: HLA-B*1402 extracellular domain, beta-2-microglobulin, Cathepsin A signal sequence octapeptide, ... (5 entities in total)
• Functional Keywords: major histocompatibility complex, mhc, human leokocyte antigen, hla, hla-b14, hla-b*1402, hla-b1402, hla-b*14, pcata, cathepsin a, ankylosing spondylitis, autoimmunity, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P61769; Lysosome: P10619
• Total number of polymer chains: 3
• Total formula weight: 45402.28

Authors

Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Uchanska-Ziegler, B.,Ziegler, A. (deposition date: 2008-01-14, release date: 2009-02-03, Last modification date: 2023-08-30)

• Primary citation: Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Merino, E.,Lopez de Castro, J.A.,Uchanska-Ziegler, B.,Ziegler, A.; Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens; J.Biol.Chem., 284:29784-29797, 2009; PubMed: 19617632; DOI: 10.1074/jbc.M109.038497

Experimental method

X-RAY DIFFRACTION (1.864 Å)