3BQO

Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex

Summary for 3BQO

Related3BU8 3BUA
DescriptorTelomeric repeat-binding factor 1, TERF1-interacting nuclear factor 2 (3 entities in total)
Functional Keywordstrf1 trfh domain dimerization domain tin2, adp-ribosylation, alternative splicing, cell cycle, cell division, chromosomal protein, dna-binding, mitosis, nucleus, phosphoprotein, telomere, dna binding protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus P54274
Nucleus. Isoform 1: Nucleus matrix Q9BSI4
Total number of polymer chains2
Total molecular weight26689.45
Authors
Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M. (deposition date: 2007-12-20, release date: 2008-02-19, Last modification date: 2011-07-13)
Primary citation
Chen, Y.,Yang, Y.,van Overbeek, M.,Donigian, J.R.,Baciu, P.,de Lange, T.,Lei, M.
A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319:1092-1096, 2008
PubMed: 18202258 (PDB entries with the same primary citation)
DOI: 10.1126/science.1151804
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.231100.5%2.2%6.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3bqo
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More Biological unit images

Molmil generated image of 3bqo
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Molmil generated image of 3bqo
rotated about x axis by 90°
Molmil generated image of 3bqo
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3bqo.pdb2.gz [38.85 KB])
Coordinate files for Biological unit (3bqo.pdb1.gz [76.14 KB])